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Ozera Copper Peptide Cream: ingredients and how to use

What is in Ozera 001 Copper Peptide Cream, ingredient by ingredient, where it fits in a routine, how to use it, and what we can and cannot tell you about it.

6 min read · By the Ozera Labs editorial team · Updated

Close view of an aloe vera plant and its pointed leaves

Ozera 001 Copper Peptide Cream is a fragrance-free moisturizer built around Copper Lysinate/Prolinate, with aloe leaf juice, glycerin and four botanical extracts. It is the cream step in a routine: apply a dime-sized amount after serum and any eye gel, morning and night, and finish the morning with your own sunscreen. Each bottle holds 1.7 fl oz / 50 ml.

This guide goes through the formula line by line, explains where the cream sits next to our other products, and is clear about what we can and cannot say. If you only want the essentials, the paragraph above is it.

Which copper ingredient is in the cream?

The copper ingredient on the label is Copper Lysinate/Prolinate: copper bound to a mixture of two amino acids, lysine and proline. Independent ingredient references describe it as a skin-conditioning ingredient and note that it is sold to brands as part of a supplier complex called Neodermyl. In our ingredient list it appears next to Methylglucoside Phosphate, the other named component of that complex.

The supplier markets the complex with claims about collagen and elastin. Those are the supplier’s claims. We have not seen independent evidence that would let us repeat them as established results, so we don’t.

One more point, because it causes real confusion: this cream does not contain Copper Tripeptide-1, the ingredient usually written GHK-Cu. Most published research on “copper peptides” is about GHK-Cu. It is a different ingredient, and we don’t borrow its evidence. Read the full explanation of the difference.

The full formula, in plain English

US labeling rules require ingredients to be listed in descending order of amount, with ingredients at 1% or less allowed to follow in any order. That means the list tells you what is present and roughly what dominates, not exact percentages.

  • Aqua — water, the base of the cream.
  • Sorbitan Olivate, Cetearyl Olivate — olive-derived emulsifiers that hold water and oil together as a cream.
  • Caprylic/Capric Triglyceride, Coco-Caprylate/Caprate — emollients that give the cream its slip and soften the feel on skin.
  • Cetyl Alcohol, Stearyl Alcohol — fatty alcohols used for texture. These are waxy thickeners, not the drying kind of alcohol.
  • Methylglucoside Phosphate, Copper Lysinate/Prolinate — the copper complex described above.
  • Cranberry fruit, Eclipta Prostrata, Moringa seed and Neem leaf extracts — botanical extracts, listed by their standardized INCI names.
  • Glycerin — a humectant, which means it attracts and holds water.
  • Aloe Barbadensis Leaf Juice — aloe leaf juice.
  • Tocopheryl Acetate — a stable form of vitamin E.
  • Totarol — a compound from the totara tree.
  • Hamamelis Virginiana (Witch Hazel) Water — witch hazel water.
  • Xanthan Gum — a thickener.
  • Alcohol — ethanol, listed near the end of the formula.
  • Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Potassium Sorbate — the preservative system that keeps a water-based product safe to use after opening.
  • Maltodextrin — a carrier, commonly used alongside plant extracts.
  • Syringa Vulgaris (Lilac) Leaf Cell Culture Extract — a plant cell culture extract.

If you know you react to witch hazel, alcohol, neem or any botanical, this list is the place to check before you buy. The same list is printed on the product page.

What “fragrance-free” means here

Our manufacturer lists this formula as fragrance-free, and you won’t find “fragrance,” “parfum” or an essential oil in the ingredient list. The cream can still have a faint natural smell from its ingredients. Fragrance-free is a formula detail, not a promise that a product will suit everyone. More on what fragrance-free does and doesn’t tell you.

Where the cream fits in a routine

This is the moisturizing step. It goes after anything thin and watery and before sunscreen.

  • Morning: cleanser → 004 Vitamin C Serum (optional) → 002 Peptide Eye Gel (optional) → Copper Peptide Cream → your sunscreen.
  • Evening: cleanser → 003 Retinol Night Serum on your chosen retinol nights → eye gel (optional) → Copper Peptide Cream.
  • Without a serum: cleanser → cream. That is a complete, reasonable routine.

The product code 001 is a name, not an instruction to use it first. Order depends on the product’s role. Our guide to application order explains the general rule.

How to use it

  1. Warm a dime-sized amount between your fingertips.
  2. Apply over your face and neck after serum and any eye gel, keeping it away from your eyes.
  3. Use it morning and night. In the morning, finish with a broad-spectrum sunscreen as directed, because this cream has no SPF.

If you are new to the formula, start using it on its own for a couple of weeks before adding anything else new. That way, if your skin disagrees with something, you know what caused it. Our guide to trying a product on a small area first covers how.

Size and price, worked out

The cream is $52 for 50 ml, which is about $1.04 per ml. When you compare moisturizers, compare price per ml as well as sticker price: a 30 ml bottle and a 50 ml bottle are not the same purchase. We don’t publish an estimate of how many days a bottle lasts, because that depends on how much you use and how often.

The cream on its own, or the Duo?

Choose the cream if the moisturizer step is what you are shopping for. The Duo pairs the same full-size cream with 004 Vitamin C Serum for a morning serum-and-cream routine, and costs $7 less than buying the two separately. Compare the Duo and the Full Routine.

What we can’t tell you

  • We don’t publish ingredient percentages, because they have not been verified to us in writing.
  • We don’t promise a visible result or a timeline. Skin varies, and a cosmetic is not a treatment.
  • We don’t hold independent certifications. “Fragrance-free” and “cruelty-free” are our manufacturer’s stated attributes.

That is deliberate. Our editorial standards explain why.

Stop using it if…

Stop if you get irritation, redness that doesn’t settle, or swelling. The cream is for external use only; keep it away from your eyes and out of reach of children. If a reaction is severe or doesn’t go away, see a doctor. You can report a reaction to us, and we will refund you without asking for the bottle back.

See the current price, full ingredient list and directions on the 001 Copper Peptide Cream page.

Photography: Emils Nemse / Unsplash.

General information, not personal medical advice. For persistent concerns or a reaction, speak with a qualified healthcare professional.